Math doesn’t have to be intimidating, especially when it’s the kind that helps fund companies and move science forward.
In this episode, host Elaine Hamm, PhD, is joined by Isaiah Reeves, PhD, Biomedical Analyst at Solas BioVentures, for a practical and approachable deep dive into venture math. Drawing on his background as a scientist turned investor, Isaiah breaks down the core financial concepts every biotech founder should understand: from valuations and dilution to IRR, cap tables, and deal terms. The conversation offers real-world guidance for navigating fundraising, choosing the right partners, and avoiding common pitfalls that can derail long-term value creation.
In this episode, you’ll learn:
- How venture capitalists think about valuations, dilution, and returns, and why fully diluted post-money matters.
- Key metrics like IRR and DPI, and how they influence investment decisions and fund performance.
- Common deal terms and cap table “red flags” founders should watch out for as they raise capital.
Tune in to learn how understanding venture math can help founders make smarter funding decisions, protect long-term value, and build biotech companies positioned for sustainable growth and impact.
Links:
Connect with
Isaiah Reeves, PhD, and check out
Solas BioVentures.
Connect with
Elaine Hamm, PhD, and learn about
Tulane Medicine Business Development and the
School of Medicine, as well as
Cadenza Bio.
Connect with
Josh Eckelberry, MBA, and
Mark Corrigan, MD.
Check out the books
The Go-Giver and
Venture Deals.
Check out the podcasts
STAT,
Biotech Hangout, and
20VC.
Check out our previous episodes on
Networking as an Introvert and
Solas BioVentures with Travis Manasco.
Connect with
Ian McLachlan, BIO from the BAYOU producer.
Learn more about
BIO from the BAYOU - the podcast.
Bio from the Bayou is a podcast that explores biotech innovation, business development, and healthcare outcomes in New Orleans & The Gulf South, connecting biotech companies, investors, and key opinion leaders to advance medicine, technology, and startup opportunities in the region.